WEBVTT 00:00.000 --> 00:00.733 By 1 week, 00:00.767 --> 00:02.600 cells of the inner cell mass 00:02.633 --> 00:04.067 form two layers called 00:04.100 --> 00:05.833 the hypoblast 00:05.867 --> 00:09.300 and epiblast. 00:09.333 --> 00:11.200 The hypoblast gives rise 00:11.233 --> 00:12.733 to the yolk sac, 00:12.767 --> 00:14.933 which is one of the structures through which 00:14.967 --> 00:16.767 the mother supplies nutrients 00:16.800 --> 00:19.600 to the early embryo. 00:19.633 --> 00:21.667 Cells from the epiblast form 00:21.700 --> 00:23.733 a membrane called the amnion, 00:23.767 --> 00:25.133 within which the embryo 00:25.167 --> 00:26.400 and later the fetus 00:26.433 --> 00:28.800 develop until birth. 00:28.833 --> 00:31.433 By approximately 2 1/2 weeks, 00:31.467 --> 00:32.967 the epiblast has formed 00:33.000 --> 00:34.867 3 specialized tissues, 00:34.900 --> 00:36.100 or germ layers, 00:36.133 --> 00:40.000 called ectoderm, 00:40.033 --> 00:44.967 endoderm, 00:45.000 --> 00:48.933 and mesoderm. 00:48.967 --> 00:50.233 Ectoderm gives rise 00:50.267 --> 00:51.767 to numerous structures 00:51.800 --> 00:53.933 including the brain, 00:53.967 --> 00:56.600 spinal cord, 00:56.633 --> 00:58.867 nerves, 00:58.900 --> 01:00.867 skin, 01:00.900 --> 01:03.600 nails, 01:03.633 --> 01:07.500 and hair. 01:07.533 --> 01:12.033 Endoderm produces the lining of the respiratory system 01:12.067 --> 01:14.567 and digestive tract, 01:14.600 --> 01:17.033 and generates portions of major organs 01:17.067 --> 01:19.633 such as the liver 01:19.667 --> 01:23.200 and pancreas. 01:23.233 --> 01:26.933 Mesoderm forms the heart, 01:26.967 --> 01:29.333 kidneys, 01:29.367 --> 01:31.833 bones, 01:31.867 --> 01:34.067 cartilage, 01:34.100 --> 01:36.333 muscles, 01:36.367 --> 01:37.933 blood cells, 01:37.967 --> 01:41.467 and other structures.