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Beginning of differentiation of the nucleolus in a 7-cell embryo

TEM of a stage 2, 7-cell embryo in vivo (original magnification x7,500). Notice the beginning of internal differentiation of the nucleolus (Nl) with segregation of fibrillar and granular material (arrows).

M = mitochondrion
N = nucleus

From: Pereda and Croxatto, 1992. Reproduced with permission of the Annals, Academy of Medicine, Singapore.

Keywords: differentiation of the nucleolus, fibrillar material, granular material, nucleolus, nucleus, seven-cell embryo, stage 2 embryo

Source: The Virtual Human Embryo.