Your Life Before Birth – Read the Story

Introduction


You and everyone you know began your lives by successfully completing the journey before birth described in Your Life Before Birth. Read on to learn more about your journey and to better understand why the prenatal experience is so important for everyone.

When you share the movie and the following images as a simple act of friendship with those who have never seen similar images before, you enable them to join the growing numbers of people enlightened and enriched by the wonders, the beauty, and the significance of every pregnancy.

I began this work in a spirit of something like active curiosity, I have prosecuted it with an ever-deepening interest, and I have brought it thus far with the growing sense that I have been dealing with a subject of tremendous importance for the future of the [human] race and the individual....

J. W. Ballantyne, M.D.
(The "Father of Prenatal Care")
Manual of Antenatal Pathology and Hygiene - The Foetus. 1902

FROM THE SCRIPT: “Welcome to the amazing world inside the womb where every tiny baby grows and prepares for life after birth. It's also the place where bonding between mother and child begins and where each little one's lifelong health is partly established.”

A very busy time and place
This active baby has recently grown just enough to touch his hands together for the first time. You can also see his left nipple (0:05–0:07), the base of his umbilical cord (0:09–0:11), and both of his hands. The straight white line along the midline of the abdomen was formed when the two sides of his trunk fused together. SOURCE: The Biology of Prenatal Development DVD (BPD video)

A word about prenatal age

All prenatal ages on this page are referenced from the start of fertilization, not the beginning of a woman's last menstrual period (LMP). To calculate the equivalent prenatal age referenced from a woman's LMP, add two weeks to the fertilization ages provided here.

A time of preparation

The nine months of pregnancy truly is a time of preparation for life after birth. With rare exception, virtually everything that a newborn baby can do has been practiced over and over again for weeks or months before birth.

A bond like no other

From the time of fertilization (or conception), the developing baby and mother seamlessly work together and communicate with one another in numerous and complex ways that are still not fully understood. Pregnancy is the ultimate expression of selfless teamwork as mother and child do everything, share everything, and experience everything together as they jointly pursue a healthy full-term pregnancy and safe delivery.

As you might expect, a mom’s health and well-being are closely intertwined with the health and well-being of her child. With few exceptions, what is good for mom is good for her baby, and what is good for her baby is good for mom. Likewise, what is harmful to mom is harmful to her baby, and what is harmful to her baby is harmful to mom.

The exceptional teamwork between mother and child begins almost immediately. The first pregnancy hormone, called early pregnancy factor, appears in mom's blood as early as 24 hours after fertilization. This hormone starts preparing her body to meet her baby’s needs.1

Prenatal growth and development influence lifelong health

Research over the past 30 years has uncovered many ways in which a baby’s prenatal environment and growth pattern influence life-long health.

…good paths of growth and development are the greatest gift society can give to the next generation.

David J. P. Barker, M.D.
Nutrition in the Womb: How better nutrition during development will prevent heart disease, diabetes, and stroke. 2008. Page 165.

To cite just a few examples, babies experiencing impaired prenatal growth face an increased risk of heart attack,2 stroke,3 hypertension,4 and Type II diabetes5 later in life. Tobacco exposure during pregnancy is associated with an increased risk of certain behavior disorders6 as well as obesity,7 diabetes,8 and diminished lung function.9

…It is evident that the fetal environment is of tremendous importance during the developmental period in determining health throughout the life of the individual.

Dr. Hugo T. Bergen
Associate Professor
Department of Anatomy and Cell Science
University of Manitoba

Fertilization – The Beginning of a New Individual


FROM THE SCRIPT: “ 'Human development begins at fertilization'10 when a male and a female reproductive cell join to form a unique, single-cell embryo.”11

Fertilization involves a series of events, which lasts about 24 hours (rather than a moment) in humans.12 Fertilization typically occurs within a woman’s uterine tube, which extends from a woman’s ovary on each side, to her uterus or womb.

Human fertilization
The single-cell human embryo is created when fertilization begins.
Single-cell embryo
This single-cell embryo shows the male and female pronuclei (the two round structures) meeting in the center. Each pronuclei contains the DNA of one parent. [Carnegie Stage 1b human embryo]

Human development and human life begin simultaneously

There are a number of unassailable scientific facts that you should know about human fertilization and the single-cell human embryo. All are important. Despite unequivocal scientific evidence, some remain controversial.

Fertilization, or conception, marks the beginning of human development; the start of a brand new, unique, genetically distinct human being; and the true onset of pregnancy.

The living, single-cell human embryo formed at fertilization is a new human life at the first stage of human development.13

Embryonic life commences with fertilization...

Ronan O'Rahilly and Fabiola Müller
Developmental Stages of Human Embryos
Carnegie Institute of Washington, 1987, Page 9.

It is to be remembered that at all stages the embryo is a living organism, that is, it is a going concern with adequate mechanisms for its maintenance as of that time.

C. H. Heuser and G. L. Streeter, 1941
Contributions to Embryology, No 181
Vol 29, No 181. Pages 15–55.

Because of the controversy, this topic deserves some further discussion.

Defining the start of human life as occurring at some point later than fertilization ignores and contradicts longstanding scientific fact. This is very simply understood. Only a continuously living embryo can divide from one cell into two, two cells into four cells, and so on throughout pregnancy. It is equally true that a dead embryo cannot grow, cannot divide, cannot change, cannot consume oxygen, cannot produce carbon dioxide, cannot replicate DNA, and cannot become alive at some future time.

Stage 1 is the unicellular embryo.... It is the beginning of embryonic life...

Raymond Gasser, Ph.D.
Principal Investigator, The Virtual Human Embryo Project
2001–2013. Stage 1. Introduction.

As a scientific question, to argue that the human embryo or fetus comes alive at some point beyond fertilization is to support a modern version of the theory of spontaneous generation. Proponents of this once-popular theory believed that living things could form from dead matter. This theory was debunked 160 years ago.

The distinction about when human life and human development begin is more than an academic or theoretical question. It has health implications. Once fertilization is underway, the fragile early embryo is susceptible to damage from the surrounding environment, which includes exposure to toxins present in mom’s uterine tube or intra-uterine environment.14

An amazing skill set

In addition to the ability to work closely with mom, the simple-appearing, single-cell human embryo directs its own development throughout life using the instruction set present in its own DNA.15

Comprehend if you can, how the most minute fragment of life—a single cell, just on the fringe of the microscopic world—can divide and redivide to make the billions and billions of cells in the body of a baby. Think of the uncountable number of tissues and organs that sprang from this initial fleck of clay: the hair, the nails, the skin, the brain, the eyes, the ductless glands. Each step of the creative process represents a series of exquisitely intricate events, each timed to the other in hairline sequence.

Better Homes and Gardens Baby Book—A Child Care and Training Guide
Meredith Publishing Company
1956. Page 15.

Multiplying and Dividing


FROM THE SCRIPT: “At about 24 hours, the single-cell embryo divides into two cells, then four cells, and so on. This begins the incredible transformation from single-cell embryo to precious newborn.”

Human embryo time-lapse (1–8 cells)
This time-lapse video shows the dynamic nature inherent in the early human embryo. Note how the individual cells are far from perfectly shaped spheres as commonly depicted.

Cell division continues. The embryo reaches 12–16 cells after about three days and is temporarily shaped like a ball of cells. At this stage, the embryo is called a morula.16

10-cell human embryo
The zona pellucida provides a protective covering around the embryo.
Human morula
The morula stage only lasts for one day or so.

As cells continue to divide, a fluid-filled cavity emerges and the embryo is now called a blastocyst.

Early human blastocyst
This early blastocyst is about 4 days post-fertilization. The cells of the inner cell mass are destined to form the embryo's body. Note that the protective shell is still in place.
Mature human blastocyst
This more mature blastocyst is about 5 days post-fertilization. The outer cells will help form the placenta. Note that the protective shell (zona pellucida) is gone.

For normal development to proceed, the blastocyst must escape its protective coating. When viewed under the microscope, this process is called "hatching." The protective coating of the human embryo developing naturally inside the womb is believed to break down and fall apart, rather than "hatch" as seen here.

Early hatching blastocyst
Here we see the embryo "escaping" the confines of the zona pellucida.
The great escape
Here you can again see the human embryo freeing itself from its protective shell.

Once free, the embryo is ready for the next big step: implantation.

Free blastocyst
This relatively large blastocyst was previously inside the adjacent protective shell.

Implantation is the process whereby the embryo leaves the cavity of the uterus by embedding itself into the wall of the uterus. This process begins on day 6 with attachment to the uterine wall and ends roughly 12 days following fertilization.

The speed and complexity with which human development unfolds may surprise you. With repeated cell divisions and various specialized cell types forming along the way, the tiny baby grows and repeatedly changes shape. Human development progresses rapidly in a highly organized fashion.

The first sign of brain development appears at 18 days.17

The mere existence of that cell [referring to the cell giving rise to the human brain] should be one of the greatest accomplishments of the earth. People ought to be walking around all day, all through their waking hours, calling to each other in endless wonderment, talking of nothing except that cell... If anyone does succeed in explaining it, within my lifetime, I will charter a skywriting airplane, maybe a whole fleet of them, and send them aloft to write one great exclamation point after another, around the whole sky, until all my money runs out!

Lewis Thomas
The Medusa and the Snail, 1979

The basic body plan featuring distinct body regions such as the head, chest region, abdomen, and the beginnings of upper and lower limbs is well established by just 4 weeks after fertilization.18

Key Periods of Prenatal Development


FROM THE SCRIPT: “You may be surprised to know that most body parts form and begin to function in the first 8 weeks, even though full-term pregnancy lasts 38 weeks.”

Human development before birth is a front-loaded process. The first 8 weeks features rapid changes in shape and appearance, along with a dramatic rise in the number of identifiable body parts. Thereafter, human development is largely marked by growth and maturation of existing body parts and functions.

Therefore, human development before birth is divided into two periods.

The embryonic period begins with fertilization and ends following the completion of 8 weeks or 56 days.19 Throughout this entire time, the developing human is properly called an embryo, meaning “growing within.”20 Most body parts and all body systems first appear during this time and begin to function.21

The fetal period begins just as soon as the embryonic period ends and continues until birth. During this time, the developing human is called a fetus, meaning “unborn offspring.”22 During the fetal period, the baby grows much larger and body functions grow more and more complex.23

The Rapidly Developing Beating Heart


FROM THE SCRIPT: “By 22 days, the heart begins to beat... and quickly resembles the heart of a newborn.”

The first sign of heart development occurs at about 20 days.24 By 22 days, the tube-shaped heart begins to beat.25Almost immediately, the heart begins changing shape as seen below.26 As we will see time and time again, the developing human begins performing new functions at what seems to be the earliest possible opportunity.

The rapidly maturing heart
Once the tubular-shaped human heart forms, it changes shape almost immediately. It is essentially fully formed within 4 weeks thereafter (or 7 weeks following fertilization).

This early onset of the baby’s heartbeat has been reported at least as early as 1962 and is not theoretical.27 Researchers have reported visualizing the subtle contractions of the tiny human beating heart using ultrasound at 23 days28 and 25 days29 after fertilization. Although once believed to be true, there is no credible modern evidence to support the onset of the beating heart at 18 days or earlier, as some have proposed.

FROM THE SCRIPT: “By 4 weeks, the baby is surrounded by a fluid-filled sac, and her heart is pumping nutrients to her entire body.”

The fluid-filled sac is a tough membrane called the amnion. The fluid within the sac is called amniotic fluid.30 Together, they protect the growing baby from trauma, help maintain fluid balances during the first half of pregnancy, and provide room for the baby to move relatively free from the force of gravity.

The circulation

FROM THE SCRIPT: “Here you can see her beating heart in slow motion just 4½ weeks after fertilization. Do you see how her heart changes color as blood enters and leaves its chambers with each beat?”

The heart begins to beat at just about the earliest possible time that it could beat. By 4 weeks, blood circulated by this tiniest of all hearts is delivering life-sustaining oxygen and nutrients to various parts of the brain and body.31 Note the precision with which this little heart does its vital work!

The brain and beating heart
The brain, heart, and liver are the most prominent structures at this stage. All are well seen here.
Beating heart in slow motion
This rare clip beautifully illustrates the precise timing and coordination needed to continuously maintain the blood supply.
The four-chambered beating heart
If you look closely, you can see contraction activity in all four heart chambers. Note how the liver fills the abdomen. The large red blood vessel that appears to be entering the liver is the umbilical vein within the umbilical cord. It is bringing oxygenated blood from the placenta to the baby. Thanks, mom!
The circulatory system faces the daunting task of having to grow and become continuously remodeled to keep pace with the embryo's overall growth while remaining fully functional in supplying the needs of the embryo's cells.

Bruce M. Carlson, M.D., Ph.D.
Human Embryology and Developmental Biology
Third edition, Philadelphia: Mosby
2004. Page 114.

Movement and Brainwaves


FROM THE SCRIPT: “By 6 weeks, the baby begins to move32 and will turn away if lightly touched on his face.33 Brainwaves have been recorded as early as 6 weeks and 2 days.”34

Movement begins

Movement begins just 5½ to 6 weeks after fertilization. It is one of our earliest activities and one of the most natural things we can do.

You may be surprised to know that movement before birth is necessary for normal development of the nerves, bones, and joints. In fact, without movement early in pregnancy, normal joint formation would be impossible.35 Movement is vital to human health, starting long before birth and at all ages thereafter.36

Exploring new features
The brain is nicely seen in this video, and the eyes are changing rapidly.

The earliest recorded brainwaves

The earliest report of brainwaves was obtained from direct measurements from an embryo estimated to be 44 days postfertilization (or 6 weeks and 2 days).37

The 7-Week Embryo


FROM THE SCRIPT: “By 7 weeks, the baby begins turning her head and moving her hands.”

Actively engaged
Active motion in the womb begins many weeks before mom can feel it. Here you can see the frontal portion of the brain, the beating heart, and active head rotation with both hands in motion at about 7 weeks following fertilization. Once again, you can see how the liver completely fills the abdomen.

Once movement begins, it doesn’t take long for many other movements of increasing complexity to emerge. These movements include coordinated muscle activity inside the body. Peristalsis is the complex traveling wave of coordinated muscle relaxation and contraction of the intestinal wall, which propels swallowed nutrients through the digestive tract. Peristalsis begins in the large intestine at 8 weeks38 and in the small intestine at 9 weeks.39

Fingers and Toes, Amazing Eyes


FROM THE SCRIPT: “Individual fingers are emerging from his hand plates… and his eyes are developing rapidly.”

The origin of fingers and toes

Distinct fingers and toes emerge from the hand and foot plates over about 10 or 11 days, starting at about 6 weeks after fertilization. It is well established that the cells between the individual fingers and toes, having served their purpose, will self-destruct through a process of planned (programmed) cell death.40

Upper and lower limb buds
The upper and lower limb buds make their first appearance at approximately 26 and 28 days, respectively. Here again, humble-appearing limb buds quickly produce magnificent structures.
Hand plate and wrist
With the passage of just 7 days, the hand and wrist regions are distinct and the hand plate is shaped like a round pancake. The marginal vein is well seen here outlining the hand plate.

Now, even more dramatic changes are about to unfold.

Hand plate
As the fingers just start to emerge, the rounded hand plate begins to flatten between the digital rays, giving the appearance of a collection of straight lines. Each digital ray will give rise to the bones of the finger (or thumb) and the corresponding metacarpal bone.
Emerging fingers
With the passage of several days, progressive "notching" of the hands unfolds with visible changes seen daily. SOURCE: The Biology of Prenatal Development video (BPD video)
Fingers
By 7½ weeks, the tissue between the fingers is gone. Individual fingers now have the freedom to move independently. Note how thick the pads of the fingers [see arrow] are in the hand of this 8-week embryo. SOURCE: BPD video
Finger movement
If you carefully watch this hand in video 13 below, you will see subtle side-to-side motion of individual fingers. This reflects early function of some of the "intrinsic" muscles of the hand (interosseus muscles).

The development of individual toes mimics that of the fingers but occurs several days later.

Eyes

The eyes at 7 weeks are well formed but still not complete. The optic nerves are forming behind each eye, along with several layers of the retina.41 Several muscles that attach to and move each eye are emerging as well.

The maturing lens
The developing lens (lens vesicle) is the most prominent feature at this stage. The lens will eventually become transparent. Its job is to bend (refract) light in order to project sharp, focused images onto the retina of objects nearby and far away.

FROM THE SCRIPT: “Leg movements are also seen... along with the startle response.”42

Legs and genital tubercle
Here you can see the legs from below. The external appearance of the genital tubercle at this stage is identical in male and female embryos.
Leg movement, startle response
Here you can see the mild notching between the toes at a time when the fingers are nearly completely separated.

FROM THE SCRIPT: “The baby’s four-chambered heart is now nearly complete43 and continues its life-sustaining activity, resting only briefly between each heartbeat.”

Heartbeat
Here you can see both ventricles contracting simultaneously.

The human heart beats approximately 54 million times before birth.44 And that is just the beginning, as EHD further estimates that the human heart beats in excess of 3.2 billion times over a typical 80-year lifespan.45

Investigators have recorded an electrical tracing of the human heart at 7½ weeks following fertilization. By this age, the conducting system within the heart is very well developed, and the EKG tracing has a very similar appearance to EKG tracings obtained from newborns and even adults.46

FROM THE SCRIPT: “By 7½ weeks, the baby’s fingers are separate. His hands begin to touch in the midline... as do his feet.”47

As his hand plates grow, the cells between the emerging fingers (and toes) undergo planned (programmed) cell death to create separation between the fingers.48 The baby’s hands can now reach and touch one another in the midline (with the feet doing likewise). This marks the beginning of exploring his world through the touch of a finger.

FROM THE SCRIPT: “Here you can see her beautiful right eye surrounded by her emerging eyelids.”

The human eye at this stage shows considerable similarity to the newborn and adult eye. Here you can see the developing lens and anterior chamber, behind which the relatively large posterior chamber is seen.

Eyelids
The eyelids are now just appearing. This is a rare chance to appreciate how advanced the eye appears at 7½ weeks, right before the eyelids begin to temporarily fuse together. The overbite is typical and temporary at this stage.

Within the posterior chamber of the eye, you can see the dark pigment of the human retina. Though not yet in final form, it has already been in place for weeks!49 You can also clearly see the early upper and lower eyelids. At this point, the eyelids begin to rapidly cover the entire surface of the eye and will soon fuse together.

The Amazing 8-Week Embryo


FROM THE SCRIPT: “Between 7 and 8 weeks, the baby forms nearly 2,000 additional body parts.”50

The sheer number of newly identifiable permanent body parts that emerge during the 7-day period from 7 weeks (or 49 days) to 8 weeks (56 days) is astounding. Despite the baby’s small size and young age, a whole new level of exquisite detail emerges as numerous individual ligaments, tendons, muscles, nerves, and blood vessels become identifiable for the first time.

The arteries of the hand

The arteries that supply the hand provide an excellent example of the exquisite detail present in the 8-week embryo. This screen shot captures the tiny arteries that supply the hand and fingers.

Hand arteries
The arteries that supply the palm of the hand and fingers are seen in this movie clip. The arterial pattern seen here precisely mimics the pattern found in newborns and adults. (Note the thick pad on the thumb and the elbow.)
Hand arteries
Just like the adult hand, the superficial arch supplies the palmar digital arteries. Each palmar digital artery splits into two digital arteries as shown here. Can you see where the palmar digital artery splits into two digital arteries?
By the end of the embryonic proper (8 postovulatory weeks), all of the major skeletal, articular, muscular, neural, and vascular elements of the limbs are present in a form and arrangement closely resembling those of the adult.

O'Rahilly R and Gardner E.
The timing and sequence of events in the development of the limbs in the human embryo.
Anat Embryol. 148(1):1-23.
1975. Page 15.

8-week embryo details
Here you can see just a few of the detailed structures visible in this cross section of an 8-week human embryo. SOURCE: Virtual Human Embryo Project, Carnegie Stage 23, section 102

The 8-week human brain

FROM THE SCRIPT: “By 8 weeks, the baby’s brain is so complex that parts of it closely resemble the brain of a newborn.”51

Parts of the brainstem (the base of the brain closest to the spinal cord) and the arterial blood supply of the brain appear very similar to those found in the newborn.

Apart from differences in proportion, the arterial pattern resembles closely that of the adult. [Referring to the arterial blood supply of the human brain 8 weeks after fertilization]

Ronan O'Rahilly and Fabiola Müller
The embryonic human brain - An atlas of developmental stages.
Second edition. New York: Wiley-Liss.
1999. Page 332.

The arrangement of the rhombencephalic nuclei and tracts at 8 weeks is very similar to that present in the newborn.

Ronan O'Rahilly and Fabiola Müller
The embryonic human brain - An atlas of developmental stages.
Third edition. New York: Wiley-Liss.
2006. Page 219.

Because the human brain is so advanced by 8 weeks, some experts believe brain function is likely already underway.

The brain at stage 23 [8 weeks postfertilization] is far more advanced morphologically than is generally appreciated, to such an extent that functional considerations are imperative....It is likely that the rapid growth of the rhombencephalon during the embryonic period proper is associated with correspondingly early functional activity.

Ronan O'Rahilly and Fabiola Müller
The embryonic human brain - An atlas of developmental stages.
Third edition. New York: Wiley-Liss.
2006. Page 219.

FROM THE SCRIPT: “The baby begins breathing movements even though there is no air in the womb. Even at this early age, most babies prefer to use their right or left hand, just like you do.”

Preparing for first breath and first cry

Breathing movements before birth help blood return to the heart and prepare the breathing muscles for their vital duties after birth. At 8 weeks, breathing motions are observed only 2% of the time.52 As the baby matures, these motions are seen roughly 30%–40% of the time.53

A full-term newborn baby has the ability to draw in her first deep breath and release her first cry because she has prepared for this moment for 30 weeks! Her many hours spent practicing breathing motions has also given her the endurance to continue breathing.

Right- and left-handedness

Ultrasound studies have shown that 75% of babies demonstrate a definite preference to move their right hands, starting 8 weeks after fertilization. The remaining babies are split into two equal groups, with one group preferring to move their left hands and the other group showing no preference.54

Eyelids
Here you can see the near-complete fusion of the eyelids. Within a few days, the white fusion line seen here will extend across the entire right eye. You can also see the light-colored collar bone adjacent to the lower right jaw and the right ear.

Appreciating what has been accomplished

FROM THE SCRIPT: “In just 8 weeks, the remarkable single-cell embryo has blossomed into one billion cells, which have already formed an estimated 4,000 body parts55 and a dozen body systems.”

The astonishing transformation in just 8 weeks is incomprehensibly complex and, considering the incalculable number of steps involved, amazingly error free.

Just imagine the excitement when you find out how many structures you can recognize in a 5-week-old embryo, barely measuring 1 cm in length. But our fascination does not stop here. The progression of changes taking place in the next 3 weeks is so rapid that at the time when the embryo measures 3 cm, all structures familiar to us are not only easily recognizable, but also already in their anatomical position. How can we hide our amazement when we realize that such a state of perfection is present in an embryo a bit longer than the distal phalanx of our little finger?

Professor Hans K. Uhthoff, M.D., FRCS(C)
The embryology of the human locomotor system
Berlin: Springer-Verlag
1990. Preface.

One immediate consequence of this dramatic developmental progress is that now more than ever, the overall form of the 8-week human embryo closely resembles the overall shape of a newborn baby despite still being a tiny fraction of a newborn’s size.

This undeniable similarity is not coincidental. Rather, it is the inevitable consequence of the fact that the 8-week embryo and the newborn baby each possess thousands of the exact same body parts, and those parts are arranged in almost exactly the same way. With these facts in mind, a similar external appearance should be expected.

The Fetal Period


The fetal period begins 8 weeks and one day after fertilization and continues until birth.

FROM THE SCRIPT: “By 9 weeks, the baby begins to suck his thumb,56 swallow,57 sigh,58 and stretch.59 His face, hands, and feet now sense and respond to light touch.”60

Active motion
The nose is normally plugged up until about 13 or 14 weeks. Note the subtle side-to-side motions of the fingers (0:05–0:06), the coiled umbilical cord (0:07), and the fused eyelids (0:11).

The early fetus continues to respond to her environment in new ways. Swallowing is a complex function that is added to the growing list of abilities being practiced before birth.

With nearly every major nerve pathway in place between the skin and the spinal cord and even to parts of the brain, the baby is already extraordinarily advanced and enters a period of rapid growth.

FROM THE SCRIPT: “Yawning begins by 9½ weeks.61 By 10 weeks, he practices walking motions and his fingerprints begin to form.”

Yawning

A yawn is no simple thing. It involves an unusually deep inspiration with slight lifting of the head, followed by a deep expiration.

Fancy footwork

The fancy footwork you see here is, of course, just the beginning. Coordinated walking motions begin long before birth, but they become more difficult to practice as the baby grows, as room inside the womb becomes extremely limited before birth.

People dance at any age.

Mikhail Baryshnikov

Dance begins
Walking and dancing motions begin long before birth!

Fingerprints

Fingerprints are unique identifiers and they are forming by 10 weeks.62

Fingernails and toenails are also beginning to grow.63

FROM THE SCRIPT: “By 11 weeks, the baby's mouth and lips are fully formed64 and she continues to grow much larger.”

There are approximately 30 muscles involved with facial expression.65 By 11 weeks, the baby begins to coordinate many of these muscles to make various expressions.66

FROM THE SCRIPT: “By 12 weeks, the baby opens and closes her mouth, and moves her tongue. Her hands are fully formed.”

In the following screen captures, we can see the tongue and roof of the mouth. Look familiar? Their appearance already very much resembles those seen in newborns.

Roof of the mouth (hard palate)
The roof of the mouth already closely resembles that seen in the newborn. The midline "fusion" line shows where the left and right sides fused together. You can also see a glimpse of the inside of the right cheek.
The tongue and roof of the mouth
This image shows the fine ridges in the roof of the mouth (the eventual hard palate). These ridges (called rugae) are normal and persist throughout life.

The nervous system continues to mature. By 13 weeks, her ability to detect a light touch extends everywhere except parts of her scalp.67

She now begins to store fat.68 The emergence of fat deposits helps the baby to fill out. Fat represents stored energy and helps the baby regulate body temperature after birth.

FROM THE SCRIPT: “As pregnancy continues, the baby continues to grow and acquire new skills. Hearing,69 sleep-wake cycles,70 responding to sound71 and light,72 forming taste preferences,73 recognizing mom’s voice,74 and more, are all a routine part of the fascinating prenatal journey.”

It was not that many years ago that doctors believed smiling did not begin until 6 weeks after birth.75 We now know that smiling, like so many other typical human behaviors, is well rehearsed, starting long before birth.

FROM THE SCRIPT: “Pregnancy is indeed a time of preparation for life after birth. It is also a time to celebrate and anticipate the joys, wonders, and challenges that come with every new life.”

Newborn Baby
This little buddy is ready for whatever comes next. Thanks again, mom. You are amazing!

FROM THE SCRIPT: “Please share this free video with your family and friends. You can download it now at: ehd.org/en.”

The Amazing Placenta and Umbilical Cord


The placenta serves as the vital interface between mother and child. It produces hormones, helps regulate the baby's body temperature, supplies oxygen, removes carbon dioxide, and more.

Placental origin of umbilical cord
This rare image shows the vessels of a functioning placenta inside the womb and shows the origin of the umbilical cord. The two vessels heading off the screen to the right connect to the umbilical vesicle (previously called yolk sac). SOURCE: BPD video
Placenta from the inside
Here you can see another inside view of the placenta. The placental vessels are centered around the origin of the umbilical cord. Like an old-fashioned telephone cord, the coiled umbilical cord can change its "length" to reach the growing baby as she moves around inside the womb. SOURCE: BPD video
The origin of the umbilical cord
This brief glimpse of the living human placenta reveals a complex array of surface vessels that sustain the growing baby. SOURCE: BPD video
Umbilical cord details
The umbilical vein brings freshly oxygenated blood to the growing baby from the placenta. Here you can see the striking color difference between the larger umbilical vein and the two smaller umbilical arteries. You can also see several placental vessels in the background. SOURCE: BPD video
Base of the umbilical cord
Loops of intestine are temporarily stored outside the body next to the base of the umbilical cord. This completely normal process is necessary because the massive liver nearly fills the entire abdomen. SOURCE: BPD video
The origin of rhythm
Every time this baby's heart beats, it creates a visible pulsation throughout the umbilical cord. SOURCE: BPD video
For questions or comments, please contact us at ehd@ehd.org.

Footnotes
1 Moore and Persaud, 2003. 33, 60; Morton et al., 1992. 72; Nahhas and Barnea, 1990. 105.
2 Barker, Winter, et al., 1989. 579; Barker DJ, 1999. 305.
3 Eriksson JG et al., 2000. 873.
4 Leon DA et al., 1996. 405.
5 Ong KK, Dunger DB, 2002. 202; International Diabetes Federation website, 2002. e-article.
6 Linnet KM et al., 2003. 1028; Braun JM et al., 2006. 1904; Millichap JG, 2008. e360; Wakschlag LS et al., 1997. 670; Fergusson DM et al., 1998. 726; Langley K et al., 2007. e-article.
7 Adams AK et al,, 2005. 396-397; Dubois and Girard, 2006. 610; von Kries R et al., 2002. 954; Power C, Jefferis BJ, 2002. 416-417; Montgomery SM, Ekbom A, 2002. 26-27.
8 Montgomery SM, Ekbom A, 2002. 26-27.
9 McEvoy CT, Spindel ER, 2017. 1-9.
10 O'Rahilly and Müller, 1987. 9. "Embryonic life commences with fertilization...."
11 O'Rahilly and Müller, 1987. 9. "Embryonic life commences with fertilization...."
12 O'Rahilly and Müller, 1987. 9. "Fertilization requires probably slightly longer than 24 hours..."; Moore and Persaud, 2003. 32; Gasser and Cork, 2001-2011. Stage 1, introduction.
13 O'Rahilly and Müller, 1987. 9; Gasser and Cork, 2001-2011. Stage 1, introduction.
14 O'Neil, 2011. 1.
15 Walsh, 1986. 157.
16 FIPAT, 2013. 145; Carlson, 2009. 44; Gasser, 1975. 1; O'Rahilly and Müller, 2001. 37; Spraycar, 1995. 1130.
17 O'Rahilly and Müller, 2006. 25.
18 O'Rahilly and Müller, 1987. 141, 143; Moore et al., 1994. 122.
19 Moore and Persaud, 2003. 3.
20 Ayto, 1990. 199.
21 O'Rahilly and Müller, 2001. 87.
22 Moore and Persaud, 2008. 2.
23 Moore and Persaud, 2008. 2; Carlson, 2009. 485.
24 Gilmour, 1941. 28; O'Rahilly and Müller, 1987. 86.
25 Campbell, 2004. 14; Carlson, 2004. 430; de Vries and Saunders, 1962. 96; Gardner and O'Rahilly, 1976. 583; Gilbert-Barness and Debich-Spicer, 1997. 650; Gittenger-de Groot et al., 2000. 17; van Heeswijk et al., 1990. 151; Kurjak, Chervenak, 1994. 439; Navaratnam, 1991. 147-148; O'Rahilly and Müller, 1987. 99; Wisser and Dirschedl, 1994. 108.
26 O'Rahilly and Müller, 1987. 99-100.
27 de Vries and Saunders, 1962. 96.
28 Wisser and Dirschedl, 1994. 108; Tezuka et al., 1991. 211. The earliest cardiac activity reported occurred at 37 postmenstrual days or 23 postfertilization days.
29 Schats et al., 1990. 989.
30 Gasser, 1975. 30; O'Rahilly and Müller, 2001. 80-81.
31 O'Rahilly and Müller, 1987. 143. "...the blood circulation is well established."
32 Birnholz et al., 1978. 539; de Vries et al., 1982. 301, 304; Humphrey, 1964. 99; Humphrey, 1970. 12; Humphrey and Hooker, 1959. 76; Humphrey and Hooker, 1961. 147; Kurjak, Chervenak, 1994. 48; Visser et al., 1992. 175-176; Natsuyama, 1991. 13; O'Rahilly and Müller, 1999a. 336; Sorokin and Dierker, 1982. 723, 726; FIPAT, 2013. 161.
33 Goodlin, 1979. D-128.
34 Borkowski and Bernstine, 1955. 363. (cited by Bernstine, 1961, 63 & 66; O'Rahilly and Müller, 1999a, 195; and van Dongen and Goudie, 1980, 193.); Hamlin, 1964. 113.
35 Uhthoff, 1990. 26.
36 Humphrey, 1970. 35; Liley, 1986. 11; Reinis and Goldman, 1980. 224.
37 Borkowski and Bernstine, 1955. 363. (cited by Bernstine, 1961, 63 & 66; O'Rahilly and Müller, 1999a, 195; and van Dongen and Goudie, 1980, 193.); O'Rahilly and Müller, 1999a. 195; van Dongen and Goudie, 1980. 193; Hamlin, 1964. 113.
38 Grand et al., 1976. 806; Pace, 1971. 77-80.
39 Cunningham et al., 1997. 169.
40 O'Rahilly and Müller, 2001. 13.
41 O'Rahilly, 1966. 31; O'Rahilly and Müller, 2001. 463; Gasser and Cork, 2001-2011. Stage 19, slides 328, 338, 352.
42 de Vries et al., 1988. 96; Visser et al., 1992. 176.
43 Cooper and O'Rahilly, 1971. 292; James, 1970. 214; Jordaan, 1979. 214; Streeter, 1948. 192; Vernall, 1962. 23. "The four chambers of the heart and the associated major vessels are externally apparent in a close approximation to their adult positions."
44 EHD, 2005. Appendix A.
45 EHD, 2005. Appendix A.
46 Straus et al., 1961. 446. (cited by Gardner and O'Rahilly, 1976, 571.): "…an electrocardiogram with the classical P, QRS, and T configuration has been obtained from a 23mm human embryo (Straus, Walker, and Cohen, 1961)."; Gardner and O'Rahilly, 1976. 583.
47 Moore et al., 1994. Table 2-1, 61; O'Rahilly and Müller, 1987. 257; Streeter, 1951. 191.
48 Moore and Persaud, 2008. Table 5-1, 80; FIPAT, 2013. 35.
49 O'Rahilly, 1966. 25.
50 EHD, 2019. 1. Internal EHD estimate.
51 O'Rahilly and Müller, 2006. 219.
52 Connors et al., 1989. 932; de Vries et al., 1982. 311; McCray, 1993. 579; Visser et al., 1992. 177.
53 Connors et al., 1989. 932; de Vries et al., 1985. 117; Patrick et al., 1980. 26, 28; Visser et al., 1992. 178.
54 Hepper et al., 1998. 531; McCartney and Hepper, 1999. 86.
55 O'Rahilly and Müller, 2001. 87.
56 Liley, 1972. 103; Liley, 1986. 13.
57 Campbell, 2004. 24; Cunningham FG et al., 2001. 149; de Vries et al., 1982. 311; Petrikovsky et al., 1995. 605.
58 de Vries et al., 1982. 305-307.
59 de Vries et al., 1982. 311; FIPAT, 2013. 170.
60 de Vries et al., 1982. 311.
61 de Vries et al., 1982. 309; FIPAT, 2013. 172.
62 Babler, 1991. 95; Penrose and Ohara, 1973. 201.
63 O'Rahilly and Müller, 2001. 170-171.
64 Timor-Tritsch et al., 1990. 291.
65 Jones, 2019. 1.
66 Valman and Pearson, 1980. 234.
67 Lecanuet and Schaal, 1996. 2; Reinis and Goldman, 1980. 232.
68 Poissonnet et al., 1983. 7; Poissonnet et al., 1984. 3. In a study of 488 fetuses, Poissonnet's group found that adipose tissue (fat) appears in the face starting in the 14th week postfertilization. By 15 weeks, fat appears in the abdominal wall, back, kidneys, and shoulders. By 16 weeks, fat is also present throughout the upper and lower limbs.
69 Lecanuet and Schaal, 1996. 5-6; Glover and Fisk, 1999. 882; Hepper and Shahidullah, 1994. F81; Querleu et al., 1989. 410;
70 American Institute of Physics, 2009. 1.
71 Glover and Fisk, 1999. 882; Hepper and Shahidullah, 1994. F81.
72 Robinson and Tizard, 1966. 52.
73 Schaal et al., 2000. 729.
74 Cheour-Luhtanen et al., 1996. 478; DeCasper and Fifer, 1980. 1174; DeCasper and Spence, 1986. 133; Gerhardt, 1990. 299; Querleu et al., 1989. 410, 417.
75 BBC News, 2004. 1.